Postoperative quality of life after laparoscopy-assisted pylorus-preserving gastrectomy compared With laparoscopy-assisted distal gastrectomy: A cross-sectional postal questionnaire survey

Highlights

• •We surveyed patients who underwent LAPPG and LADGBI via questionnaire using newly developed questionnaire, the PGSAS-45.
• •LAPPG is superior to LADGBI for maintaining QOL.
• •LAPPG is recommended for cT1N0 middle third gastric cancer.

Background

Little is known about postgastrectomy syndrome and quality of life (QOL after laparoscopy-assisted pylorus-preserving gastrectomy (LAPPG). The aim of this study was to assess postgastrectomy syndrome and QOL after LAPPG as compared with laparoscopy-assisted distal gastrectomy with Billroth-I reconstruction (LADGBI).

Conclusion

LAPPG is superior to LADGBI for ameliorating postgastrectomy syndrome and maintaining QOL. LAPPG is recommended for patients with cT1N0 middle third gastric cancer.

http://www.americanjournalofsurgery.com/article/S0002-9610(16)30653-5/abstract

 

Influence of perineural invasion in predicting overall survival and disease-free survival in patients With locally advanced gastric cancer

 

Highlights

• •Perineural invasion (PNI) is an important pathologic feature of neoplasms.
• •Influence of PNI is used for staging in different types of tumors.
• •Prognosis of gastric cancer patients is shown to be influenced by PNI.
• •PNI should be considered to plan the best systemic treatment after surgery

Background

The aim of the present study was to evaluate the prognostic significance of perineural invasion (PNI) in locally advanced gastric cancer patients who underwent D2 gastrectomy and adjuvant chemotherapy.

Conclusions

PNI and T stage and positive lymph nodes are independent markers of poor prognosis in patients with gastric cancer. PNI should be incorporated in the postoperative staging system for planning follow-up after surgery and in our opinion to propose more aggressive postoperative therapies in PNI-positive patients.

http://www.americanjournalofsurgery.com/article/S0002-9610(16)30367-1/abstract
 

Sentinel Node Mapping Using a Fluorescent Dye and Visible Light During Laparoscopic Gastrectomy for Early Gastric Cancer: Result of a Prospective Study From a Single Institute

Lee, Chang Min MD, PhD; Park, Sungsoo MD, PhD; Park, Seong-Heum MD, PhD; Jung, Sung Woo MD, PhD; Choe, Jung Wan MD; Sul, Ji-Young MD, PhD; Jang, You Jin MD, PhD; Mok, Young-Jae MD, PhD; Kim, Jong-Han MD, PhD

Annals of Surgery: April 2017 - Volume 265 - Issue 4 - p 766–773

doi: 10.1097/SLA.0000000000001739

Original Articles

Objective: The aim of this study was to investigate the feasibility of sentinel node mapping using a fluorescent dye and visible light in patients with gastric cancer.

Background: Recently, fluorescent imaging technology offers improved visibility with the possibility of better sensitivity or accuracy in sentinel node mapping.

Methods: Twenty patients with early gastric cancer, for whom laparoscopic distal gastrectomy with standard lymphadenectomy had been planned, were enrolled in this study. Before lymphadenectomy, the patients received a gastrofiberoscopic peritumoral injection of fluorescein solution. The sentinel basin was investigated via laparoscopic fluorescent imaging under blue light (wavelength of 440–490 nm) emitted from an LED curing light. The detection rate and lymph node status were analyzed in the enrolled patients. In addition, short-term clinical outcomes were also investigated.

Results: No hypersensitivity to the dye was identified in any enrolled patients. Sentinel nodes were detected in 19 of 20 enrolled patients (95.0%), and metastatic lymph nodes were found in 2 patients. The latter lymph nodes belonged to the sentinel basin of each patient. Meanwhile, 1 patient (5.0%) experienced a postoperative complication that was unrelated to sentinel node mapping. No mortality was recorded among enrolled cases.

Conclusions: Sentinel node mapping with visible light fluorescence was a feasible method for visualizing sentinel nodes in patients with early gastric cancer. In addition, this method is advantageous in terms of visualizing the concrete relationship between the sentinel nodes and surrounding structures.

http://journals.lww.com/annalsofsurgery/Abstract/2017/04000/Sentinel_Node_Mapping_Using_a_Fluorescent_Dye_and.24.aspx