Changes of Esophagogastric Junctional Adenocarcinoma and Gastroesophageal Reflux Disease Among Surgical Patients During 19882012: A Single-institution, High-volume Experience in China

Liu, Kai MD^*; Yang, Kun MD^*; Zhang, Weihan MD^*; Chen, Xiaolong MD^*; Chen, Xinzu MD^*; Zhang, Bo MD, PhD^*; Chen, Zhixin MD^*; Chen, Jiaping MD^*; Zhao, Yongfan MD^†; Zhou, Zongguang MD, PhD, FACS^*; Chen, Longqi MD, PhD^†; Hu, Jiankun MD, PhD^*

Annals of Surgery: January 2016 - Volume 263 - Issue 1 - p 88–95

doi: 10.1097/SLA.0000000000001148

Original Articles

Objective: To evaluate the changes of esophagogastric junctional adenocarcinoma (EGJA) and gastroesophageal reflux disease (GERD) among surgical patients from 1988 to 2012 in a Chinese high-volume hospital.

Background: The incidence of EGJA in Western countries has rapidly increased in recent decades. However, recent data from China remain sparse.

Conclusions: An increasing trend of EGJA is observed during the past 25 years in West China Hospital. The prevalence of GERD among EGJA had showed a gradually increased trend. However, the causality between GERD and EGJA still needs to be researched further. Total gastrectomy is becoming more preferred procedure in patients with EGJA.

http://journals.lww.com/annalsofsurgery/Fulltext/2016/01000/Changes_of_Esophagogastric_Junctional.15.aspx